Thermodynamic Analysis oh Chiral Separations in Normal Phase HPLC
Document Type
Article
Abstract
The enantiloselectivity of mandelic acid and various optically active derivatives on a chiral stationary phase in normal phase HPLC was previously investigated. The study revealed that chiral centers with certain functional groups require bridging with methyl or ethyl groups for separation to occur. This observation is being investigated through thermodynamic analysis of two series of analytes in the same mobile phase with a view towards determining the enthalpic and entropic contributions to adsorption.
Recommended Citation
Chu, Cindy, "Thermodynamic Analysis oh Chiral Separations in Normal Phase HPLC" (2005). Honors Independent Research Papers. 21.
https://digitalcommons.pace.edu/honorsindependent_researchpapers/21
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Comments
Only the ABSTRACT of this paper is being made available at this time. Original date of submission of this paper is 2000.